Joe Kiani, Masimo
Joe Kiani, Masimo

Scaling a chronic care startup requires more than breakthrough technology. It calls for a deep understanding of long-term engagement, sustained behavior change, and care models that fit seamlessly into daily life. Success depends not only on what the platform can do, but how well it supports people over time. Joe Kiani, Masimo and Willow Laboratories founder, is backing this kind of growth through solutions like Nutu™, which blend real-time support with behavioral science. His approach moves beyond innovation for its own sake, focusing instead on measurable outcomes, sustainable change, and meaningful impact.

Chronic conditions like diabetes, hypertension, and obesity demand a long-term view. The startups addressing them must think beyond features and functionality. They must build adaptability, collaboration with providers, and user support that evolves with real-life needs. This is how digital health moves from promising to lasting.

Real-Time Support Over Episodic Intervention

Traditional care models rely on touchpoints, appointments, labs, and prescriptions. Chronic care is continuous, not episodic. The startups that scale successfully understand this and design their platforms to support people in the day-to-day rhythm of their health decisions.

Startups like Nutu are built on real-time data integration. Wearables and connected apps allow users to receive personalized prompts when it matters most, like before a meal, during a stressful moment, or after disrupted sleep. This moment-based support keeps users engaged and helps reduce long-term risk through small, consistent behavior changes. Scaling this kind of care means building systems that work not just during onboarding or peak usage but all year long.

Simplicity Wins User Loyalty

Sophisticated backends don’t always equal user success. Startups that succeed at scale know that a platform has to be easy to use, even for those who may not consider themselves tech-savvy. Nutu was designed with minimal input demands.

It runs quietly in the background, surfaces short insights, and offers nudges in plain language. Simplicity is critical for people managing complex conditions. Startups looking to grow in chronic care must prioritize accessibility in their user experience, making the product feel intuitive rather than instructional.

Engagement Beyond Downloads

Many health apps see a spike in usage at the beginning, followed by a rapid drop-off. Chronic care startups that scale understand that true success lies in retention, not just reach. To achieve this, platforms must deliver consistent value, especially beyond the first few weeks.

For example, Nutu adapts to user behavior over time. If a person typically skips morning activity, the app adjusts its feedback. If glucose patterns improve, it reinforces those wins. This developing, personalized experience keeps users coming back because it reflects their progress, not a generic plan.

Personalization at Scale

Scaling personalized care is a challenge, but not an impossible one. With the right AI and behavioral frameworks, startups can deliver context-specific insights that feel tailored, even when reaching thousands of users. Platforms achieve this by analyzing multi-stream data, such as glucose, sleep, activity, and stress.

Each insight is shaped by the user’s patterns, not just their diagnosis. The feedback changes depending on how the user behaves, not just based on demographic data or static profiles. Startups that scale in this space succeed by offering personal support without requiring individual customization every step of the way.

Building Provider Trust

Chronic care doesn’t happen in isolation. For a platform to scale, it needs to have clinical credibility. Providers want accurate, actionable tools that complement, not compete with, their existing workflows.

It supports this by offering shareable summaries and real-time user data that providers can review to adjust care plans.

These reports are designed to be easy to read and useful in a clinical setting, not just a consumer interface. Startups that win in chronic care partner with providers, not just patients, ensuring their platform fits within a broader care ecosystem.

Earning User Trust with Transparency

Scaling also means building long-term trust. People are handing over sensitive health information. They want to know how it’s used and why. Startups must be clear about their intentions and protective of user data from day one.

Nutu does this by showing users where insights come from and allowing them to control notification settings and data-sharing preferences. This level of transparency increases trust and reduces churn.

In a field where trust drives engagement, startups that scale successfully take privacy and consent seriously, not as fine print but as core product features.

Supporting Habit, Not Perfection

Chronic conditions are not solved in a week. Startups that grow in this space understand that their goal isn’t rapid change, but sustainable progress. They support habit formation, behavior adaptation, and psychological momentum.

Joe Kiani, Masimo founder, points out, “Our goal with Nutu is to put the power of health back into people’s hands by offering real-time, science-backed insights that make change not just possible, but achievable.”  That philosophy is built into the app’s design, helping users recognize progress, even in small steps, and offering reinforcement rather than reprimand. Startups that grow in chronic care scale because they work with the user, not just for them.

Interoperability as an Accelerator

Chronic care doesn’t live in a single app. Users often juggle multiple tools, medication trackers, step counters, sleep apps and more. The startups that scale fastest are those that connect easily with other platforms.

Success is tied in part to an app’s ability to integrate wearables, CGMs, and other health devices. The goal isn’t to replace everything else, but to make sense of the signals that are already collected. This approach lowers the barrier to entry and adds value without creating new friction.

Scaling With Intention

Growing a chronic care startup requires more than technology. It requires trust, empathy, design thinking, and clear communication. It means building products that help users live with their condition rather than feel controlled by it. By focusing on real-time value, sustainable habits, and outcomes that matter, startups aren’t just scaling. They’re transforming how we approach chronic care, making it smarter, more personal, and more human.